Exploring the Link Between Mould Exposure and Autism
Let's dive into something fascinating – the connection between mould exposure and autism. You know, some types of moulds, also known as fungi, can produce these not-so-friendly compounds called mycotoxins. And guess what? These little troublemakers have been linked to not only physical issues but also things like neurological problems, tummy troubles, and inflammation.
Here's the deal: some mycotoxins can mess with our gut, making it easier for harmful stuff to sneak into our bloodstream. Not only does this mess with our immune system, but it also messes with how our brain works through what's called the gut-brain axis. To make matters worse, mycotoxins can shake up the balance of good and bad bacteria in our gut and turn up the inflammation dial, basically paving the way for all sorts of health problems.
Kids with autism seem to have higher levels of a mycotoxin called ochratoxin A (OTA) in their bodies compared to their non-autistic siblings and control groups. What's intriguing is that even though they eat similar foods and are exposed to similar things, those with autism seem to have a harder time getting rid of these mycotoxins. This suggests there might be some issues going on with how their bodies process and detoxify toxins.
So, how do we get exposed to these pesky moulds and mycotoxins? Well, it can happen in different ways – like eating contaminated food or breathing in mouldy air. Mould loves hanging out in damp places, like bathrooms, fabrics, dishwashers, and even behind sinks and pipes. And when it comes to indoor mould, think about names like Aspergillus, Cladosporium, and Penicillium.
And wait, here comes the surprise – some of our favourite foods can also play host to these not-so-fun moulds. Think grains, cheese, nuts, dried beans, fruits, mushrooms, packaged meats, and even our beloved coffee and alcohol beverages.
But let's say you find out you're in the middle of a mould exposure situation. What should you do? First things first, cut down on your exposure. You can get your place checked by pros using swab tests or fancy air quality monitors. A tailored diet plan aimed at limiting key sources of mould intake and improving the detoxification process should be considered. And hey, don't forget about those friendly probiotics with Lactobacillus – they can lend a helping hand too.
To wrap it up, the story of mould exposure and autism is like a puzzle with lots of pieces. But by taking steps to dodge mould, tweaking our diet, and giving our body a detox boost, we're on a path towards better understanding and, hopefully, better health.
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References:
Barbara De Santis, Carlo Brera, Alessandra Mezzelani, Sabina Soricelli, Francesca Ciceri, Giorgio Moretti, Francesca Debegnach, Maria Clara Bonaglia, Laura Villa, Massimo Molteni & Maria Elisabetta Raggi (2019) Role of mycotoxins in the pathobiology of autism: A first evidence, Nutritional Neuroscience, 22:2, 132-144, DOI: 10.1080/1028415X.2017.1357793
Kraft, S., Buchenauer, L., & Polte, T. (2021). Mold, Mycotoxins and a Dysregulated Immune System: A Combination of Concern?. International journal of molecular sciences, 22(22), 12269. https://doi.org/10.3390/ijms222212269
Serkan, Y., Beyazit, U., & Ayhan, A. B. (2021). Mycotoxin Exposure and Autism: A Systematic Review of the Molecular Mechanism. Current molecular pharmacology, 14(5), 853–859. https://doi.org/10.2174/1874467213999200819145942